Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells

2001 ◽  
Vol 81 (1) ◽  
pp. 102-113 ◽  
Author(s):  
Jau-Shyang Huang ◽  
Jinn-Yuh Guh ◽  
Hung-Chun Chen ◽  
Wen-Chun Hung ◽  
Yung-Hsiung Lai ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Advanced Glycation ◽  
Collagen Production ◽  
Advanced Glycation End Product ◽  
Stat Signaling

Phytochemicals against anti‐diabetic complications: targeting the advanced glycation end product signaling pathway

2021 ◽  
Vol 44 (4) ◽  
pp. 378-401
Author(s):  
Amna Parveen ◽  
Razia Sultana ◽  
Seung Min Lee ◽  
Tae Hun Kim ◽  
Sun Yeou Kim
Keyword(s):  
Signaling Pathway ◽  
Diabetic Complications ◽  
Advanced Glycation ◽  
Advanced Glycation End Product

scholarly journals Study on the role of JAK/STAT signaling pathway during chicken spermatogonial stem cells generation based on RNA-Seq

2015 ◽  
Vol 14 (5) ◽  
pp. 939-948 ◽  
Author(s):  
Lei ZHANG ◽  
Qi-sheng ZUO ◽  
Dong LI ◽  
Chao LIAN ◽  
Kamel E Ahmed ◽  
...  
Keyword(s):  
Stem Cells ◽  
Signaling Pathway ◽  
Spermatogonial Stem Cells ◽  
Rna Seq ◽  
Stat Signaling

scholarly journals SP103PROTECTION ROLE OF AUTOPHAGY IN ADVANCED GLYCATION END PRODUCT-INDUCED MESENGIAL CELL INJURY

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii412-iii412
Author(s):  
Chien-Ling Lee ◽  
Tien-Fong Lu ◽  
Chih Kang Chiang ◽  
Shing Hwa Liu
Keyword(s):  
Cell Injury ◽  
Advanced Glycation ◽  
Advanced Glycation End Product

scholarly journals JAK/STAT Activation: A General Mechanism for Bone Development, Homeostasis, and Regeneration

2020 ◽  
Vol 21 (23) ◽  
pp. 9004
Author(s):  
Alexandra Damerau ◽  
Timo Gaber ◽  
Sarah Ohrndorf ◽  
Paula Hoff
Keyword(s):  
Signaling Pathway ◽  
Bone Development ◽  
Gene Knockout ◽  
Selective Inhibition ◽  
Janus Kinase ◽  
General Mechanism ◽  
Stat Signaling ◽  
Skeletal Phenotype ◽  
Pro Inflammatory Cytokines

The Janus kinase (JAK) signal transducer and activator of transcription (STAT) signaling pathway serves as an important downstream mediator for a variety of cytokines, hormones, and growth factors. Emerging evidence suggests JAK/STAT signaling pathway plays an important role in bone development, metabolism, and healing. In this light, pro-inflammatory cytokines are now clearly implicated in these processes as they can perturb normal bone remodeling through their action on osteoclasts and osteoblasts at both intra- and extra-articular skeletal sites. Here, we summarize the role of JAK/STAT pathway on development, homeostasis, and regeneration based on skeletal phenotype of individual JAK and STAT gene knockout models and selective inhibition of components of the JAK/STAT signaling including influences of JAK inhibition in osteoclasts, osteoblasts, and osteocytes.

Role of VHL-JAK-STAT signaling pathway in central nervous system hemangioblastoma associated with von Hippel-Lindau disease

2020 ◽  
Vol 148 (1) ◽  
pp. 29-38 ◽  
Author(s):  
Hiroshi Kanno ◽  
Tetsuya Yoshizumi ◽  
Masamichi Shinonaga ◽  
Atsuhiko Kubo ◽  
Hidetoshi Murata ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Signaling Pathway ◽  
Von Hippel Lindau ◽  
Stat Signaling ◽  
Von Hippel Lindau Disease ◽  
Central Nervous System Hemangioblastoma
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